Flovent Inhaler

- Pulmonary Sequelae at Six Months following Extracorporeal Membrane Oxygenation (12)

It is commonly believed that the avoidance of further injury from treatment, using lung rest on ECMO, will allow lung healing and recovery. However, the results from this study suggest that these infants have such severe initial lung injury that chronic lung disease cannot be completely prevented by this mode of therapy.
In this study, 42 percent of infants had Pa02 <80 mm Hg. Further, 47 percent of infants required supplemental oxygen at some time during the first six months of life. Krummel et al reported normal Pa02 in six ECMO survivors who were breathing room air, and none was noted to be clinically cyanotic. However, the infants in the study of Krummel et al were studied at 10 to 15 months of age, while our patients were studied at 6 months of age. It is possible that oxygenation will improve with increasing age in some of our patients as well. Andrew et al reported that 31 percent of infants required supplemental oxygen during the first year of life, which is similar to our information on younger infants. Fifty-two percent of our patients were treated by bronchodilators, and 32 percent were placed on oral diuretics for clinical signs of chronic lung disease. None of the infants in the previously noted two studies received any diuretics or bronchodilators.

August 24, 2013 Pulmonary function
Tags: chronic lung disease mechanical ventilation neonatal respiratory failure pulmonary function respiratory failure