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- Pulmonary Sequelae at Six Months following Extracorporeal Membrane Oxygenation (11)

Pulmonary Sequelae at Six Months following Extracorporeal Membrane Oxygenation (11)However, only one of the infants required rehospitalization during the first six months for respiratory deterioration. Additionally, chronic lung disease following ECMO was less severe in this group when compared with that in preterm BPD infants at a similar age. The most common abnormalities were increased Raw and decreased SGaw. These findings were further confirmed by the fact that the most commonly required medication was a bronchodilator (52 percent). Therefore, ECMO and lung rest may modify the severity of chronic lung disease, but do not appear to prevent it altogether, as previously suggested.
Long-term pulmonary function abnormalities are well recognized following neonatal respiratory failure secondary to lung injury from prematurity, neonatal pneumonia and meconium aspiration syndrome. However, the exact mechanisms and factors contributing to chronic lung disease are not completely understood. Considerable evidence is available to suggest a major role of treatment modalities, such as supplemental oxygen and mechanical ventilation. All infants treated by ECMO were exposed to high concentrations of oxygen and mechanical assisted ventilation for 44 ± 9 h prior to initiation of ECMO.

August 21, 2013 Pulmonary function
Tags: chronic lung disease mechanical ventilation neonatal respiratory failure pulmonary function respiratory failure